System and method for biomarker-outcome prediction and medical literature exploration
US11257594B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 17, 2021 |
| Grant date | Feb 22, 2022 |
| Priority date | — |
| Expiry date | Feb 17, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06F2216/03
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A system and method for biomarker-outcome prediction and medical literature exploration which utilizes a data platform to analyze, optimize, and explore the knowledge contained in or derived from clinical trials. The system utilizes a knowledge graph and data analysis engine capabilities of the data platform. The knowledge graph may be used to link biomarkers with molecules, proteins, and genetic data to provide insight into the relationship between biomarkers, outcomes, and adverse events. The system uses natural language processing techniques on a large corpus of medical literature to perform advanced text mining to identify biomarkers associated with adverse events and to curate a comprehensive profile of biomarker-outcome associations. These associations may then be ranked to identify the most-common biomarker-outcome association pairs. Having a comprehensive profile of ranked biomarker-outcome data allows the system to predict biomarkers associated with a given disease and serious adverse events linked to biomarker data.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.