Microscopy imaging device with advanced imaging properties

US11259703B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Kunal Ghosh · San Francisco, US
• Laurie Burns · Menlo Park, US
• Abbas El Gamal · Palo Alto, US
• Mark J. Schnitzer · Summit, US
• Eric Cocker · Redwood City, US
• Tatt Wei Ho · Stanford, US

Key dates

• Filing date: Oct 26, 2020
• Grant date: Mar 1, 2022
• Expiry date: Oct 26, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H30/40
• WIPO field: Audio-visual technology
• WIPO sector: Electrical engineering

Abstract

Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.