TRNA synthetase inhibitors
US11261201B2 · kind B2 · utility
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27Claims
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Assignee
Inventors
Key dates
| Filing date | Jan 11, 2019 |
| Grant date | Mar 1, 2022 |
| Priority date | — |
| Expiry date | Jan 11, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are secondary amine compounds that inhibit tRNA synthetase. The compounds of the invention are useful in inhibiting tRNA synthetase in Gram-negative bacteria and are useful in killing Gram-negative bacteria. The secondary amine compounds of the invention are also useful in the treatment of tuberculosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.