Glycosylated antitumor ether lipids as novel cancer stem cell cytotoxic agents
US11261210B2 · kind B2 · utility
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Key dates
| Filing date | Feb 8, 2013 |
| Grant date | Mar 1, 2022 |
| Priority date | — |
| Expiry date | Feb 8, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Glycosylated antitumor ether lipids (GAELs) are effective cytotoxic agents against cancer stem cells. Furthermore, combining GAELs which kill cells by a caspase-independent pathway with agents that kill cells by apoptosis will lead to elimination of the differentiated tumor cells and the undifferentiated cancer stem cells leading to an elimination of the tumor and preventing recurrence.
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