Methods for producing preparations of recombinant AAV virions substantially free of empty capsids
US11261463B2 · kind B2 · utility
1Cited by
7References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 12, 2019 |
| Grant date | Mar 1, 2022 |
| Priority date | — |
| Expiry date | Oct 1, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography techniques and provide for commercially viable levels of recombinant AAV virions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.