Methods and compositions for enrichment of target nucleic acids
US11261479B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Apr 23, 2019 |
| Grant date | Mar 1, 2022 |
| Priority date | — |
| Expiry date | Oct 27, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure relates to a method of target enrichment and amplification of selective target regions of genomes or nucleic acid samples and further analysis by systems such as NGS. The disclosure provides methods and kits that can be used in numerous downstream procedures including DNA sequencing. The disclosed methods can be utilized to sequence the target nucleic acid sequences such as to detect the presence of genetic variations for biological assays, assessment of disease, to count copies of target regions, and to allow such target enrichment prior to sequencing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.