Activation assay for the diagnosis of a heparin-induced thrombocytopenia

US11262357B2 · kind B2 · utility

Assignee

• Siemens Healthcare Diagnostics Products GmbH · DE

Inventors

• Harald Althaus · Wetter, DE
• Gerlinde Christ · Marburg, DE
• Herbert Schwarz · Niedereschach, DE
• Michaela Wicke · Fritzlar, DE
• Norbert Zander · Marburg, DE

Key dates

• Filing date: Jun 8, 2018
• Grant date: Mar 1, 2022
• Expiry date: Feb 14, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/226
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to a functional, easily automatable assay for establishing a heparin-induced thrombocytopenia (HIT). What is measured is the secretion of PF4 (platelet factor 4) from activated thrombocytes.