Method for increasing cell proliferation in pancreatic beta cells, treatment method, and composition
US11266647B2 · kind B2 · utility
5Cited by
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24Claims
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Key dates
| Filing date | Oct 26, 2017 |
| Grant date | Mar 8, 2022 |
| Priority date | — |
| Expiry date | Oct 26, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/999
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method of increasing cell proliferation in a population of pancreatic beta cells and a method of treating a subject for a condition associated with an insufficient level of insulin secretion. Also disclosed is a composition. The composition includes a dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1 A) inhibitor and a transforming growth factor beta (TGFP) superfamily signaling pathway inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.