Nucleic acids encoding engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene
US11266693B2 · kind B2 · utility
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Key dates
| Filing date | Sep 9, 2020 |
| Grant date | Mar 8, 2022 |
| Priority date | — |
| Expiry date | Sep 9, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/03
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human T cell receptor alpha constant region gene. The present disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.