Patent · US Active

Tetrahydro-1H-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2α inhibitors

US11267782B2 · kind B2 · utility

4Cited by
5References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 30, 2021
Grant dateMar 8, 2022
Priority date
Expiry dateMar 30, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2603/97
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure provides certain tetrahydro-1H-cyclopenta[cd]indene compounds that are Hypoxia Inducible Factor 2α (HIF-2α) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of HIF-2α. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.