Class of amino-substituted nitrogen-containing fused ring compounds, preparation method therefor, and use thereof
US11267815B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Oct 30, 2018 |
| Grant date | Mar 8, 2022 |
| Priority date | — |
| Expiry date | Dec 15, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a class of amino-substituted nitrogen-containing fused ring compounds, a preparation method therefor, and a use thereof. The structure of the amino-substituted nitrogen-containing fused ring compounds of the present invention is as shown in formula (I) below, and each group therein is as defined in the specification. The amino-substituted nitrogen-containing fused ring compounds of the present invention are novel specific FGFR kinase inhibitors, having excellent inhibitory activity for FGFR-related tumor cell proliferation, and is applicable to the treatment of diseases such as tumors associated with FGFR kinase mutations or abnormal expressions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.