Patent · US Active

Non-aggregating immunostimulatory oligonucleotides

US11268098B2 · kind B2 · utility

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13Claims
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Key dates

Filing dateDec 24, 2015
Grant dateMar 8, 2022
Priority date
Expiry dateJan 24, 2036

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are non-aggregating immunostimulatory oligonucleotides. The present invention also provides a delivery agent for an immunostimulatory-oligonucleotide nucleic acid medicine, said delivery agent including a nucleic acid that contains a phosphorothioated nucleotide. According to another aspect, the present invention further provides an oligonucleotide including a bioactive core, and a nucleic acid that contains a phosphorothioated nucleotide. The present invention yet further provides an immunostimulator including the bioactive core of a type A/D, type B/K, or type C immunostimulatory oligonucleotide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.