Non-aggregating immunostimulatory oligonucleotides
US11268098B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 24, 2015 |
| Grant date | Mar 8, 2022 |
| Priority date | — |
| Expiry date | Jan 24, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are non-aggregating immunostimulatory oligonucleotides. The present invention also provides a delivery agent for an immunostimulatory-oligonucleotide nucleic acid medicine, said delivery agent including a nucleic acid that contains a phosphorothioated nucleotide. According to another aspect, the present invention further provides an oligonucleotide including a bioactive core, and a nucleic acid that contains a phosphorothioated nucleotide. The present invention yet further provides an immunostimulator including the bioactive core of a type A/D, type B/K, or type C immunostimulatory oligonucleotide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.