IL-15 and IL-15RAPLHA sushi domain based immunocytokines
US11273204B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Aug 8, 2014 |
| Grant date | Mar 15, 2022 |
| Priority date | — |
| Expiry date | Aug 8, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an immunomodulatory antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Rα or derivatives thereof; and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.