Adenoviral coat protein derived delivery vehicles
US11274127B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Mar 31, 2017 |
| Grant date | Mar 15, 2022 |
| Priority date | — |
| Expiry date | Aug 11, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An engineered adenovirus penton base protomer, wherein the penton base protomer comprises a first RGD-loop, a second RGD-loop, a variable loop (V loop), an Adenovirus fiber protein binding cleft, and an N-terminal domain; wherein at least one of the first RGD-loop, the second RGD-loop, and the V loop comprises at least one inserted non-adenoviral antigenic polypeptide; and wherein the engineered adenovirus penton base protomer is capable of assembling into virus-like particles (VLPs).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.