Compositions and methods for inhibiting factor D
US11274307B2 · kind B2 · utility
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33References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2020 |
| Grant date | Mar 15, 2022 |
| Priority date | — |
| Expiry date | Jan 14, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The application discloses methods and compositions for the inhibition of the alternative complement pathway. The methods and compositions involve the use of aptamers for inhibiting complement Factor D. The application further provides anti-Factor D aptamers for the treatment of dry age-related macular degeneration, geographic atrophy, wet age-related macular degeneration or Stargardt disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.