Structured substrates for optical surface profiling

US11275030B2 · kind B2 · utility

Assignee

• TRUSTEES OF BOSTON UNIVERSITY · US

Inventors

• M. Selim Ünlü · Newton, US
• David A. Bergstein · Brookline, US
• Michael Ruane · Hopedale, US
• Bennett B. Goldberg · Newton, US

Key dates

• Filing date: Dec 27, 2019
• Grant date: Mar 15, 2022
• Expiry date: Dec 27, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/061
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

This disclosure provides methods and devices for the label-free detection of target molecules of interest. The principles of the disclosure are particularly applicable to the detection of biological molecules (e.g., DNA, RNA, and protein) using standard SiO2-based microarray technology.