Successive sampling device and associated method

US11275084B2 · kind B2 · utility

Assignees

• Stanford University · US
• Robert Bosch GmbH · DE

Inventors

• Sam Kavusi · Menlo Park, US
• Daniel Roser · St. Georgen, DE
• Christoph Lang · Palo Alto, US
• AmirAli Haj Hossein Talasaz · San Francisco, US

Key dates

• Filing date: Jan 15, 2010
• Grant date: Mar 15, 2022
• Expiry date: Apr 18, 2037

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L3/5027
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method of determining a number of a solution constituent includes introducing a first number of solution constituents to a first test location, establishing a first binding environment for the introduced first number of solution constituents, creating a first residual number of solution constituents by binding a first plurality of solution constituents, establishing a second binding environment for the first residual number of solution constituents, creating a second residual number of solution constituents by binding a second plurality of solution constituents from the first residual number of solution constituents, obtaining a first signal associated with the bound first plurality of solution constituents, obtaining a second signal associated with the bound second plurality of solution constituents, and determining a second number of a constituent of interest based upon the obtained first signal and the obtained second signal.