Patent · US Active

Sustained release solid dosage forms for modulating the colonic microbiome

US11278498B2 · kind B2 · utility

1Cited by

5References

16Claims

0Family size

Assignee

Axial Therapeutics, Inc. · US

Inventors

Ryan Barrett · San Francisco, US
Hitesh R. Bhagat · Wayland, US
Anthony Stewart Campbell · Framingham, US

Key dates

Filing date	Nov 5, 2020
Grant date	Mar 22, 2022
Priority date	—
Expiry date	Nov 5, 2040

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described are sustained-release solid dosage forms of epigallocatechin gallate (EGCG) or aminosterol compositions. In one aspect of the invention the sustained-release solid dosage forms of EGCG or an aminosterol are capsules comprising a plurality of coated solid particulates. Another aspect of the invention relates to methods of inhibiting, ameliorating, reducing the likelihood of, delaying the onset of, treating or preventing an amyloid disorder, comprising the step of administering to a subject in need a therapeutically effective amount of the solid dosage form. In certain aspects, the amyloid disorder is Parkinson's Disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.