Process for producing an organic compound

US11279955B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Hartwig Schroeder · Greytown, ZA
• Stefan Haefner · Speyer, DE
• Oskar Zelder · Speyer, DE
• Christoph Wittmann · Saarlouis, DE
• Anna Christine Schroer · Ludwigshafen, DE
• Birgit Hoff · Ludwigshafen, DE
• Nico Boehmer · Ludwigshafen, DE

Key dates

• Filing date: May 18, 2018
• Grant date: Mar 22, 2022
• Expiry date: Jul 22, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/01
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Described herein is a process of producing an organic compound, the process including: I) cultivating a genetically modified microorganism in a culture medium including sucrose as an assimilable carbon source to allow the genetically modified microorganism to produce the organic compound, and II) recovering the organic compound from the fermentation broth obtained in process step I) The genetically modified microorganism includes A) at least one genetic modification that leads to an increased activity of the enzyme encoded by the rbsK-gene, compared to the original microorganism that has not been genetically modified, and the original microorganism belongs to the family Pasteurellaceae. Also described herein are a genetically modified microorganism and the use thereof for the fermentative production of an organic compound from sucrose as an assimilable carbon source.