Polymer microparticle-based method for probe deposition in label-free biosensors
US11280782B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Feb 8, 2016 |
| Grant date | Mar 22, 2022 |
| Priority date | — |
| Expiry date | Mar 27, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/545
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a sensor chip for detecting a target molecule in a sample. The sensor chip includes a substrate having a surface and a layer of hydrogel particles immobilized on the substrate surface at two or more locations on the surface, wherein the hydrogel particles at a first location comprise a plurality of first probe molecules bound to the particles and the hydrogel particles at a second location comprise a plurality of second probe molecules bound to the particles. Systems that include the sensor chip, as well as methods of preparing and using the sensor chip, are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.