Synthetic polymeric implantable artificial cornea device incorporating nanopatterns

US11284991B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Albert Yee · Irvine, US
• Marjan Farid · Irvine, US
• Roger F. Steinert · North Andover, US
• Elena Liang · Irvine, US
• Mary Nora Dickson · Brooks Road, US

Key dates

• Filing date: Mar 10, 2017
• Grant date: Mar 29, 2022
• Expiry date: Aug 25, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/16
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

In various embodiments, disclosed herein is an artificial cornea, comprising an optic zone that is similar in thickness to a natural cornea and a peripheral skirt having a thickness less than the thickness of the optic zone, where the surfaces of the optic zone and peripheral skirt comprise one or more microstructures or nanostructures. In various embodiments, further disclosed herein are methods of manufacturing nanostructures on an artificial cornea, as well as treating a disease by providing an artificial cornea having one or more microstructures and/or nanostructures.