Process for manufacturing porous silica particles loaded with at least one bioactive compound adapted for lung, nasal, sublingual, and/or pharyngeal delivery
US11285107B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 3, 2018 |
| Grant date | Mar 29, 2022 |
| Priority date | — |
| Expiry date | May 3, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/183
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for manufacturing porous silica particles comprising at least one bioactive compound, whereby the particles are adapted for lung, nasal, sublingual and/or pharyngeal delivery of said at least one bioactive compound and have an MMAD between 0.5 and 15 μm with a GSD less than 2.5. The invention also relates to a pharmaceutical composition comprising said silica particles and a use of the silica particles in the diagnoses, prevention and/or treatment of local and/or systemic disorders, such as disorders of the lung, nose, sublingual and/or pharynx.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.