Methods and compositions for RNA-guided treatment of HIV infection
US11285193B2 · kind B2 · utility
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Key dates
| Filing date | Jan 29, 2018 |
| Grant date | Mar 29, 2022 |
| Priority date | — |
| Expiry date | Oct 17, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/21
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating a subject at risk for having a virus infection, by administering to the subject a prophylactically effective amount of a composition comprising a vector encoding a CRISPR-associated endonuclease and at least two guide RNAs, wherein the guide RNAs are complementary to two target sequences spanning from the 5′- to 3′-LTRs of the sequence in the virus, and preventing a retroviral infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.