Patent · US Active

Separation matrices for purification of biological particles

US11285460B2 · kind B2 · utility

0Cited by

5References

11Claims

0Family size

Assignee

Cytiva BioProcess R&D AB · SE

Inventors

Jean-Luc Maloisel · Uppsala, SE
Karolina Busson · Uppsala, SE
Karol Lacki · Uppsala, SE
Bjorn Noren · Uppsala, SE
Helena Skoglar · Uppsala, SE

Key dates

Filing date	Feb 18, 2015
Grant date	Mar 29, 2022
Priority date	—
Expiry date	Aug 7, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N1/20
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

The invention discloses a separation matrix for purification of biological particles, comprising a plurality of particles having a porous core entity and a porous shell entity covering the core entity, wherein the core entity comprises at least 50 micromole/ml primary amines present on covalently attached ligands displaying at least two primary amines per ligand and the shell entity comprises less than 20 micromole/ml primary amines The invention further discloses a method of purifying biological particles and a method of manufacturing a separation matrix.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.