Pyrazine-2(1H)-ketone compound acting as FGFR inhibitor

US11286248B2 · kind B2 · utility

Assignee

• ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD. · CN

Inventors

• Yang Zhang · San Diego, US
• Zhifei Fu · Shanghai, CN
• Miaorong Luo · Shanghai, CN
• Zaifang REN · Shanghai, CN
• Dongjie HU · Lo Wu, CN
• Jie Li · Shanghai, CN
• Jian Li · Shanghai, CN
• Shuhui CHEN · Shanghai, CN

Key dates

• Filing date: Feb 2, 2019
• Grant date: Mar 29, 2022
• Expiry date: Apr 11, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are a compound as shown in formula (I), and an isomer thereof or a pharmaceutically acceptable salt thereof, and involved is the use thereof in the preparation of drugs for treating FGFR-associated diseases.