Type I and type III interferon fusion molecules and methods for use thereof
US11292823B2 · kind B2 · utility
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2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 1, 2018 |
| Grant date | Apr 5, 2022 |
| Priority date | — |
| Expiry date | Jul 4, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fusion molecules composed of a type I interferon protein or portion thereof and a type III interferon protein or portion thereof, pharmaceutical compositions containing the fusion molecules, and methods for their use in inhibiting infection, inhibiting or treating cancer, inducing signaling of transcription of IFN-stimulated genes through an IFN-αR2 chain in a subject suffering from an infection which degrades or downregulates an IFN-αR1 chain, and treating various diseases or conditions are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.