Patent · US Active

Cell culture apparatus and culture methods using same

US11293002B2 · kind B2 · utility

0Cited by

0References

17Claims

0Family size

Inventors

Frederic Zenhausern · Fountain Hills, US
Paul Wilmes · Dudelange, LU
Pranjul Shah · Esch-sur-Alzette, LU

Key dates

Filing date	May 27, 2016
Grant date	Apr 5, 2022
Priority date	—
Expiry date	Aug 12, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12M35/08
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Cell culture apparatus for emulating gastrointestinal tract conditions and comprising at least two adjacent, microfluidic, cell cultivation channels separated by a permeable or semipermeable membrane, a first channel carrying gastrointestinal tract epithelial cells or tissues and a second channel carrying luminal and preferably mucosal microbiota, and wherein said second channel comprises one or more dwell chambers capable of providing a location for unattached luminal flora to reside away from any direct flow in said second channel, permits modelling of multiple sections of the gastrointestinal tract and control of retention times.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.