Antisense antibacterial compounds and methods

US11293024B2 · kind B2 · utility

Assignees

• The Board of Regents of the University of Texas System · US
• Oregon State University · US

Inventors

• Bruce L. Geller · Corvallis, US
• David Greenberg · Omer, IL

Key dates

• Filing date: Dec 23, 2015
• Grant date: Apr 5, 2022
• Expiry date: Dec 23, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2320/31
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are antisense oligonucleotides targeted against bacterial genes involved in biochemical pathways and/or cellular processes, and related compositions and methods of using the oligonucleotides and compositions, alone or in combination with other antimicrobial agents, for instance, in the treatment of an infected mammalian subject.