Method for labeling of aldehyde containing target molecules
US11293060B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Oct 8, 2019 |
| Grant date | Apr 5, 2022 |
| Priority date | — |
| Expiry date | Dec 16, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2563/113
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to improving the processing rate of a sequencing reaction, for example in a nanopore sequencing reaction, by means of using improved nucleoside-tags. The tags are linked to the nucleoside phosphate via a Pictet Spengler reaction. Exemplary sequencing reactions that are improved by the present methods include nanopore-based nucleic acid sequencing-by-synthesis reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.