System and method for measuring vibrational spectra in living cells and tissue over time
US11293853B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 10, 2019 |
| Grant date | Apr 5, 2022 |
| Priority date | — |
| Expiry date | Sep 10, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06F2218/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are systems and methods for measuring vibrational spectra of a living cells and tissue that includes a low noise consistent optical source creating a photon beam, a support device, a photon-to-electron converter/detector outputting a streamed analog electrical signal, an analog-to-digital converter, and a digital signal processor with specialized software for measuring and characterizing the signal contained in the photon beam and its subsequent detector's streamed analog converted to digital signal. Motion of the living sample causes modulation to the photon beam as it passes through the living samples by how much of the photon beam is blocked, absorbed or deflected. In addition, specific sub-cellular vibrational features can be segregated utilizing fluorescent markers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.