Halogenated fullerene functionalized as a biocidal and chemotactic spermicide to vaginally harbor and neutralize spermatozoa for use as a safe and effective contraceptive
US11298375B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Oct 12, 2021 |
| Grant date | Apr 12, 2022 |
| Priority date | — |
| Expiry date | Oct 12, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides the methods and composition useful as a contraceptive by preventing motile sperm from reaching a mature ovum, thereby blocking fertilization and preventing pregnancy. The contraceptive is comprised of halogen functionalized fullerene nanoparticles (halo fullerenes) and chemotactic stimulants that act synergistically to divert, incapacitate and ultimately rupture spermatozoa to avert fertilization. When applied vaginally prior to coitus, the suspension is activated by exposure to spermatozoa upon insemination. Notably, non-spermatozoa cells are unaffected by the pH-neutral suspension; however, closer to the same scale, microbes are susceptible to its inherent biocidal properties. Following application and coitus, the contraceptive evacuates naturally, along with seminal and vaginal fluids thereafter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.