Cellular adjuvants for viral infection
US11298414B2 · kind B2 · utility
3Cited by
2References
8Claims
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Assignee
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Key dates
| Filing date | Aug 9, 2019 |
| Grant date | Apr 12, 2022 |
| Priority date | — |
| Expiry date | Aug 9, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/16034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Two-component vaccine formulations and methods are contemplated where the vaccine has an adjuvant component and a therapeutic component. The therapeutic component comprises preferably a recombinant therapeutic virus encoding a therapeutic antigen while the adjuvant component comprises a non-host cell or immune stimulating portion thereof. Notably, use of the adjuvant component will result in significant uptake of the therapeutic component into immune competent cells, even in the absence of receptors for entry of the therapeutic component. In addition, such adjuvant also stimulates expression of the therapeutic antigen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.