Synthesis of key intermediate of KRAS G12C inhibitor compound
US11299491B2 · kind B2 · utility
12Cited by
50References
1Claims
0Family size
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Key dates
| Filing date | Nov 15, 2019 |
| Grant date | Apr 12, 2022 |
| Priority date | — |
| Expiry date | Feb 1, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C309/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.