Thermostable polymerase inhibitor compositions and methods
US11299739B2 · kind B2 · utility
1Cited by
9References
16Claims
0Family size
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Key dates
| Filing date | Jun 6, 2017 |
| Grant date | Apr 12, 2022 |
| Priority date | — |
| Expiry date | Dec 21, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2525/205
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure relates to aptamers for temperature-dependent reversible inhibition of thermostable polymerase activity in order to improve sensitivity and specificity of various reactions and assays involving hot start polynucleotide synthesis. Methods for use of the aptamers and related compositions and kits are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.