Methods and devices related to amplifying nucleic acid at a variety of temperatures

US11299776B2 · kind B2 · utility

Assignee

• The Board of Regents of the University of Texas System · US

Inventors

• Andrew Ellington · Austin, US
• Cheulhee Jung · Daejeon, KR
• Sheng CAI · Corona, US
• Sanchita BHADRA · Austin, US
• John Milligan · Philadelphia, US
• Daniel J. Garry · Richwood, US
• Raghav Shroff · Austin, US

Key dates

• Filing date: May 10, 2018
• Grant date: Apr 12, 2022
• Expiry date: May 10, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed are compositions and methods for nucleic acid amplification and detection. Specifically, disclosed herein are compositions and methods that allow for amplification of nucleic acids at a wide variety of temperatures. This includes a polymerase which is thermostable at high temperatures, and a method of amplification that can be conducted at relatively low temperatures.