Protein reporters for ultrasensitive detection methods
US11300640B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Mar 13, 2018 |
| Grant date | Apr 12, 2022 |
| Priority date | — |
| Expiry date | Mar 13, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A90/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions and methods using protein reporters as imaging agents in 129Xe NMR and MRI applications. It is described that bla and MBP are genetically-encoded proteins that induce a detectable chemical shift during 129Xe NMR, allowing for use as protein reporters in research and clinical applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.