Use of I-BRD9 or derivatives thereof in preparing anti-epileptic drugs

US11304935B2 · kind B2 · utility

Assignee

• University of South China · CN

Inventors

• Wenyu Cao · Nanhu, CN
• Yang Xu · Wenhe, CN
• Dan Luo · Ithaca, US
• Wei Wan · Shanghai, CN
• Jie He · Newton, US
• Xiaolin Zhong · Hunan, CN
• Xi Chen · Beijing, CN
• Zhenghai LIU · Hunan, CN
• Jiayu ZENG · Lanzhou, CN
• Zhen Wang · Shanghai, CN
• Hui YANG · Taipei, TW
• Lei Niu · Shanghai, CN
• Shishi Luo · Hunan, CN

Key dates

• Filing date: Sep 25, 2019
• Grant date: Apr 19, 2022
• Expiry date: Sep 29, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are methods of using bromodomain-containing protein 9 inhibitor (I-BRD9) or a derivative thereof in preparation of anti-epileptic drugs. The I-BRD9 has significant effects on anticonvulsion, prolonging of convulsion latency, and reduction of seizure level, and can be used for preparing anti-epileptic drug preparations.