Avian influenza and fowl adenovirus type 4 bi-combined genetic engineering subunit vaccine and method for preparing the same
US11305006B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 13, 2021 |
| Grant date | Apr 19, 2022 |
| Priority date | — |
| Expiry date | Sep 13, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/84
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure relates to the technical field of veterinary biological products, and discloses an avian influenza and fowl adenovirus type 4 bi-combined genetic engineering subunit vaccine. An antigen in the vaccine is a fusion antigen; the fusion antigen has a) avian influenza virus HA protein; b) fowl adenovirus fiber2 protein; c) a specific linker peptide located between the avian influenza virus HA protein and the fowl adenovirus fiber2 protein; the amino acid sequence of the specific linker peptide is as shown in SEQ ID NO:2. This vaccine contains the fusion antigen which can induce poultries to produce a high-level specific antibody to protect poultries from avian influenza and fowl adenovirus infection. Meanwhile, the disclosure also discloses a method for preparing the vaccine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.