Surfactant microbubbles and process for preparing and methods of using the same
US11305013B2 · kind B2 · utility
0Cited by
2References
12Claims
0Family size
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Inventors
Key dates
| Filing date | Aug 25, 2015 |
| Grant date | Apr 19, 2022 |
| Priority date | — |
| Expiry date | Nov 13, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/1098
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to an ultrasound contrast agent (UCA) comprising an outer shell and a gas core. The gas core is filled with oxygen, and the outer shell comprises a first surfactant and a second surfactant. The invention also relates to a method of making an oxygen-filled UCA and delivering oxygen to a local area of a subject's body. The method comprises injecting a composition comprising an oxygen-filled UCA of the invention into the subject's body; directing ultrasound radiation to the local area in an intensity sufficient to rupture the UCA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.