Process for producing fluorinated compounds using alcohol solvent having unsaturated hydrocarbon
US11306091B2 · kind B2 · utility
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Key dates
| Filing date | May 29, 2020 |
| Grant date | Apr 19, 2022 |
| Priority date | — |
| Expiry date | May 29, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for producing an organofluoro compound including [18F]fluorine, and by using a solvent represented by Formula 1 in nucleophilic fluorination reaction, an organofluoro compound may be prepared at a high yield. In addition, since the solvent has very excellent solubility for a precursor compound, the solvent is suitable for the automated synthesis of 18F-labeled radiopharmaceuticals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.