Patent · US Active

Anti-CD40 antibodies and uses thereof

US11306149B2 · kind B2 · utility

1Cited by
48References
20Claims
0Family size

Assignees

Inventors

Key dates

Filing dateDec 27, 2018
Grant dateApr 19, 2022
Priority date
Expiry dateDec 27, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/94
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40 and comprise improved heavy and light chain variable regions that impart improved yield and reduced aggregation. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.