Electrochemical sensors with a chemically attached molecular redox buffer

US11307165B2 · kind B2 · utility

Assignee

• Regents of the University of Minnesota · US

Inventors

• Jinbo Hu · Shanghai, CN
• Philippe Pierre Joseph Buhlmann · Minneapolis, US
• Andreas Stein · Schneverdingen, DE
• Xue Zhen · Minneapolis, US

Key dates

• Filing date: Jul 20, 2017
• Grant date: Apr 19, 2022
• Expiry date: Oct 27, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N27/333
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Solid-contact electrodes include a molecular redox buffer that is covalently attached to one of the components of the electrodes. These electrodes can be incorporated into electrochemical sensor systems. The electrode components are an electron conductor, a membrane and optionally, an interlayer. The electrode includes covalent attachment of the molecular redox buffer to the interlayer, to the electron conductor or the membrane. The interlayer includes nanoporous carbon such as CIM-carbon. The molecular redox buffer includes a well-defined redox pair, e.g., a complex of Co(II)/Co(III). The electrodes are ion-selective electrodes (ISEs) or reference electrodes. Methods include constructing solid contact electrodes and using the electrodes in electrochemical sensor systems to determine the quantity of an analyte in a sample. The electrochemical sensor systems include disposable paper-based devices and/or wearable devices for measuring analytes in a sample.