Methods of particle manipulation and analysis

US11307170B2 · kind B2 · utility

Assignees

• THE TRUSTEES OF PRINCETON UNIVERSITY · US
• UT-BATTELLE, LLC · US
• UNIVERSITY OF HAWAII · US

Inventors

• Jesse AULT · Knoxville, US
• Sangwoo Shin · Princeton, US
• Howard A. Stone · Princeton, US
• Jie Feng · Beijing, CN
• Patrick B. Warren · Bebington, GB

Key dates

• Filing date: Jun 29, 2020
• Grant date: Apr 19, 2022
• Expiry date: Jul 16, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2015/0053
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods described herein, in some embodiments, permit extraction of particle structural and/or surface charge data from gradient induced particle motion in channels. In one aspect, a method of manipulating particle motion comprises introducing a fluid into a channel, the fluid comprising particles, and driving particle accumulation to a preselected location in the channel by setting advective velocity of the fluid to offset diffusiophoretic mobility of the particles at the preselected location.