Patent · US Active

Compositions and methods for antigen detection incorporating inorganic nanostructures to amplify detection signals

US11307198B2 · kind B2 · utility

1Cited by

0References

2Claims

0Family size

Assignee

WASHINGTON STATE UNIVERSITY · US

Inventors

Yuehe Lin · Troy, US
Dan Du · Pullman, US
Yang Song · Kunming, CN
Ranfeng Ye · Pullman, US

Key dates

Filing date	Apr 24, 2017
Grant date	Apr 19, 2022
Priority date	—
Expiry date	Oct 19, 2037

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/00
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The disclosure relates to antigen detection reagents and related methods, systems, and kits. The reagents comprise an antigen-binding molecule conjugated to an inorganic component. In some embodiments, the inorganic component possesses catalytic functionality to provide a detectable signal. In some embodiments, the catalytic inorganic component is or comprises a bimetallic nanoparticle. In other embodiments, the inorganic component is a nanoflowers that provides a physical scaffold onto which the antigen-binding component and a reporter component can be loaded, resulting in augmented antigen-binding and reporting capabilities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.