Patent · US Active

Antigen-specific T cell receptors and T cell epitopes

US11311611B2 · kind B2 · utility

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1References

16Claims

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Assignees

BioNTech Cell & Gene Therapies GmbH · DE
Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz Gemeinnützige GmbH · DE

Inventors

Ugur Sahin · Mainz, DE
Ozlem Tureci · Homburg, DE
Petra Simon · Mainz, DE
Tana Omokoko · Mainz, DE

Key dates

Filing date	Sep 4, 2018
Grant date	Apr 26, 2022
Priority date	—
Expiry date	Mar 5, 2040

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/916
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T cell receptors having a defined MHC restriction and to identify immunologically relevant T cell epitopes. Furthermore, the present invention relates to antigen-specific T cell receptors and T cell epitopes and their use in immunotherapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.