Targeting nanoparticles
US11312685B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 27, 2018 |
| Grant date | Apr 26, 2022 |
| Priority date | — |
| Expiry date | May 17, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/1812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein is a composition comprising a plurality of liposomes having an average diameter of less than 400 nanometers, wherein the plurality of liposomes comprise: a first lipid or phospholipid; a second lipid or phospholipid which is derivatized with a polymer; and a sterically bulky excipient capable of stabilizing the liposomes; a third lipid or phospholipid derivatized with a polymer terminated with an integrin targeting component; DSPE or a fourth lipid or phospholipid derivatized with a group binding a contrast enhancing agent wherein the plurality of liposomes optionally encapsulates a payload component consisting of one or more bioactive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.