Patent · US Active

Pseudomonas aeruginosa PcrV binding single variable domain antibodies

US11312788B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignee

Ablynx N.V. · BE

Inventors

Evelyn De Tavernier · Deurle, BE
Ann Union · Aalter, BE
Bruno Dombrecht · Heusden, BE
Guy Hermans · Merelbeke, BE
Erika Morizzo · Wondelgem, BE

Key dates

Filing date	Jul 17, 2018
Grant date	Apr 26, 2022
Priority date	—
Expiry date	Apr 4, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Polypeptides are provided that are capable of significantly inhibiting and/or neutralizing P. aeruginosa. The polypeptides comprise two or more immunoglobulin single variable domains that are directed against the PcrV protein of P. aeruginosa, wherein the “first” immunoglobulin single variable domain and the “second” immunoglobulin single variable domain have different paratopes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.