Method for diagnosing amyotrophic lateral sclerosis using signal peptide as indicator
US11313862B2 · kind B2 · utility
5Cited by
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12Claims
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Key dates
| Filing date | Mar 2, 2017 |
| Grant date | Apr 26, 2022 |
| Priority date | — |
| Expiry date | Dec 6, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A90/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The method for aiding ALS detection provided by the present invention includes determining a profile of signal peptides contained in a bodily fluid from a test subject, and comparing the signal peptide profile thus determined for the test subject with a previously-determined profile of signal peptides in a bodily fluid from a healthy subject. The presence of a difference between the signal peptide profile of the test subject and the signal peptide profile of the healthy subject at a specific molecular weight is then associated with the test subject's suffering from or developing ALS.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.