Dual container system for product reconstitution

US11318069B2 · kind B2 · utility

Assignees

• Baxter International Inc. · US
• Baxter Healthcare SA · CH

Inventors

• Yuanpang Samuel Ding · Libertyville, US
• Ying-Cheng Lo · North Aurora, US
• Jacob Daniel Rivett · Round Lake, US
• Grant Anthony Bomgaars · Kildeer, US
• Thomas E. Dudar · Palatine, US
• Mark Edward Pasmore · Grayslake, US
• Michael Joseph Sadowski · Ringwood, US
• Anastasios Hristakos · Evanston, US
• Joseph V. Ranalletta · Guntersville, US
• Bernd Krause · Liederbach, DE

Key dates

• Filing date: Jul 12, 2018
• Grant date: May 3, 2022
• Expiry date: Oct 9, 2038

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01D69/08
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

A system for reconstituting and sterilizing a concentrate includes a mixing container, a filtration device, and a product bag. The a mixing container has an inlet port and outlet port in fluid communication with a mixing chamber disposed between the inlet port and the outlet port. The mixing chamber is adapted to contain a product concentrate. The filtration device has an inlet and an outlet, the inlet of the filtration device coupled to the outlet port of the mixing container. The filtration device includes a filter membrane with a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm. The product bag has an inlet port coupled to the outlet of the filtration device, and has a bladder defining an empty sterile chamber for receiving sterilized and reconstituted product resulting from mixing a diluent with a product concentrate in the mixing chamber to obtain a mixture then introduced through the filtration device to obtain the reconstituted and sterilized product.