Patent · US Active

Oral pharmaceutical composition of Tecovirimat and preparation method thereof

US11318115B2 · kind B2 · utility

0Cited by

1References

16Claims

0Family size

Assignee

INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY, ACADEMY OF MILITARY MEDICAL SCIENCES · CN

Inventors

Wu Zhong · Beijing, CN
Meiyan Yang · Beijing, CN
Wei Gong · Burnaby, CA
Yuli Wang · Tianjin, CN
Chunsheng Gao · Beijing, CN
Xinbo Zhou · Beijing, CN
Song Li · Beijing, CN

Key dates

Filing date	Jul 4, 2017
Grant date	May 3, 2022
Priority date	—
Expiry date	Oct 20, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08L5/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a pharmaceutical composition, comprising Tecovirimat, cyclodextrin and an additive, and optionally a pharmaceutically acceptable excipient. The present invention also relates to a method for preparing the pharmaceutical composition. The composition improves the solubility of Tecovirimat in water by using cyclodextrin and meglumine in combination, as compared with the solubility of Tecovirimat in water by using cyclodextrin or meglumine alone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.